| Bioactivity | Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. Endosidin2 inhibits exocytosis and endosomal recycling in both plant and human cells and enhances plant vacuolar trafficking. Endosidin2 is a valuable new tool for the study of exocytosis[1]. | ||||||||||||
| Name | Endosidin-2 | ||||||||||||
| CAS | 1839524-44-5 | ||||||||||||
| Formula | C15H12FIN2O3 | ||||||||||||
| Molar Mass | 414.17 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Zhang C, et al. Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis. Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E41-50. |
Endosidin-2
CAS: 1839524-44-5 F: C15H12FIN2O3 W: 414.17
Endosidin2 (ES2) binds to the exocyst component of 70 kDa (EXO70) subunit of the exocyst complex with a Kd of 253 μM. E
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