| Bioactivity | (Z)-PUGNAc is a potent O-GlcNAcase inhibitor. (Z)-PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E form[1]. | |||||||||
| Invitro | (Z)-PUGNAc amplifies the incorporation of O-GlcNAc on proteins within both HeLa and HEK cell systems[1]. | |||||||||
| Name | (Z)-PUGNAc | |||||||||
| CAS | 132489-69-1 | |||||||||
| Formula | C15H19N3O7 | |||||||||
| Molar Mass | 353.33 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Perreira M, et al. Inhibition of O-GlcNAcase by PUGNAc is dependent upon the oxime stereochemistry. Bioorg Med Chem. 2006;14(3):837-846. |
(Z)-PUGNAc
CAS: 132489-69-1 F: C15H19N3O7 W: 353.33
(Z)-PUGNAc is a potent O-GlcNAcase inhibitor. (Z)-PUGNAc is a vastly more potent inhibitor of O-GlcNAcase than the E for
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