| Bioactivity | Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm)[1][2]. |
| Invitro | Elsinochrome A (0-3 μM，5 min) 可降低 B16 细胞的存活率、诱导细胞内 ROS 产生、诱导自噬体形成并在光照下诱导细胞凋亡[1]。Elsinochrome A (0.3-3 μM, 5 min) 定位于 B16 细胞的线粒体[1]。Elsinochrome A (0-32 μg/mL，24 或 48 小时) 在光照射时显示出针对白色念珠菌的抗真菌活性[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Elsinochrome A 相关抗体: RT-PCR[1] Cell Line: |
| CAS | 24568-67-0 |
| Formula | C30H24O10 |
| Molar Mass | 544.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yao Y, et al. Elsinochrome A induces cell apoptosis and autophagy in photodynamic therapy. J Cell Biochem. 2023 Sep;124(9):1346-1365. [2]. Pan L, et al. Inhibitory Effects and Mechanism of Action of Elsinochrome A on Candida albicans and Its Biofilm. J Fungi (Basel). 2022 Aug 11;8(8):841. |
Elsinochrome A
CAS: 24568-67-0 F: C30H24O10 W: 544.51
Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis
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This product is for research use only, not for human use. We do not sell to patients.