Bioactivity | Elamipretide (MTP-131) is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide. Elamipretide can improves left ventricular and mitochondrial function in dogs with advanced heart failure[1]. | ||||||
Target | Cardiolipin peroxidase | ||||||
Name | Elamipretide | ||||||
CAS | 736992-21-5 | ||||||
Sequence | {d-Arg}-{Dmt}-Lys-Phe-NH2 | ||||||
Shortening | {d-Arg}-{Dmt}-KF-NH2 | ||||||
Formula | C32H49N9O5 | ||||||
Molar Mass | 639.79 | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Reference | [1]. Sabbah HN et al. Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure. Circ Heart Fail. 2016 Feb;9(2):e002206. |