| Bioactivity | EP3 antagonist 6 (compound 5) is a potent, orally and selective EP3 receptor antagonist, with an IC50 of 1.9 nM. EP3 antagonist 6 can inhibits PGE2-induced (HY-101952) uterine contraction in pregnant rats[1]. |
| Name | EP3 antagonist 6 |
| CAS | 499149-94-9 |
| Formula | C31H37NO4 |
| Molar Mass | 487.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Asada M, et, al. 3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 3: Synthesis, metabolic stability, and biological evaluation of optically active analogs. Bioorg Med Chem. 2010 May 1;18(9):3212-23. |
EP3 antagonist 6
CAS: 499149-94-9 F: C31H37NO4 W: 487.63
EP3 antagonist 6 (compound 5) is a potent, orally and selective EP3 receptor antagonist, with an IC50 of 1.9 nM. EP3 ant
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