Bioactivity | Edoxaban M4, an active metabolite of Edoxaban, shows reproducible, but concentration-dependent matrix effects. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor [1][2]. | ||||||||||||
Name | Edoxaban M4 | ||||||||||||
CAS | 834919-19-6 | ||||||||||||
Formula | C22H25ClN6O5S | ||||||||||||
Molar Mass | 520.99 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Romain Siriez, et al. Importance of measuring pharmacologically active metabolites of edoxaban: development and validation of an ultra-high-performance liquid chromatography coupled with a tandem mass spectrometry method. J Thromb Thrombolysis. 2020 Apr;4 [2]. Kathrin I Foerster, et al. Simultaneous quantification of direct oral anticoagulants currently used in anticoagulation therapy. J Pharm Biomed Anal. 2018 Jan 30;148:238-244. |