| Bioactivity | CDK5-IN-3 (compound 11) is a potent and selective CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD)[1]. | ||||||||||||
| Name | CDK5-IN-3 | ||||||||||||
| CAS | 2639542-32-6 | ||||||||||||
| Formula | C22H26N4O | ||||||||||||
| Molar Mass | 362.47 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Discovery and Optimization of Highly Selective Inhibitors of CDK5. J Med Chem. 2022 Feb 24;65(4):3575-3596. |
CDK5-IN-3
CAS: 2639542-32-6 F: C22H26N4O W: 362.47
CDK5-IN-3 (compound 11) is a potent and selective CDK5 inhibitor, with IC50s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/C
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This product is for research use only, not for human use. We do not sell to patients.