PeptideDB

ERα degrader 8

CAS: 2971837-95-1 F: C27H21NO5 W: 439.46

ERα degrader 8 (Compound 18j) is a selective Estrogen Receptor degrader. ERα degrader 8 is degrader to MCF-7 cells wit
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Bioactivity ERα degrader 8 (Compound 18j) is a selective Estrogen Receptor degrader. ERα degrader 8 is degrader to MCF-7 cells with IC50 value of 0.15 μM[1].
CAS 2971837-95-1
Formula C27H21NO5
Molar Mass 439.46
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Lu Y, et al. Discovery of novel quinoline scaffold selective estrogen receptor degraders (SERDs) for treatment of ER positive breast cancer with enhanced antiproliferative bioactivity through immunogenic cell death (ICD) effects. European Journal of Medicinal Chemistry, 2024: 116534.