| Bioactivity | EMD 53998 is a cardiotonic agent that increases myocardial contractility as an inhibitor for phosphodiesterase III (PDE III) and a calcium sensitizer. EMD 53998 increases myocardial contractility, reduces energy consumption and the risk of inducing arrhythmias[1]. | ||||||||||||
| CAS | 120223-04-3 | ||||||||||||
| Formula | C22H23N3O4S | ||||||||||||
| Molar Mass | 425.50 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Lues I, et al., The two mechanisms of action of racemic cardiotonic EMD 53998, calcium sensitization and phosphodiesterase inhibition, reside in different enantiomers. J Cardiovasc Pharmacol. 1993 Jun;21(6):883-92. |
EMD 53998
CAS: 120223-04-3 F: C22H23N3O4S W: 425.50
EMD 53998 is a cardiotonic agent that increases myocardial contractility as an inhibitor for phosphodiesterase III (PDE
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