Bioactivity | EM-12-Alkyne-C6-OMs is a conjugate of E3 ligase ligand and linker, consisting of 2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12) (HY-138793) and the corresponding Linker (HY-159018). EM-12-Alkyne-C6-OMs can be used to synthesize PROTACs[1]. |
CAS | 2570254-42-9 |
Formula | C22H26N2O6S |
Molar Mass | 446.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhu X, et al. Addressing the Enzyme-independent tumor-promoting function of NAMPT via PROTAC-mediated degradation. Cell Chem Biol. 2022 Nov 17;29(11):1616-1629.e12. |