8-CPT-2'-O-Me-cAMP_product_DataBase

Bioactivity	8-CPT-2'-O-Me-cAMP is a Rap1 activator. 8-CPT-2'-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration[1].
Target	Rap1
Invitro	8-CPT-2'-O-Me-cAMP (250 µM; 1 h) 诱导 Rap1 活化并增强视网膜色素上皮细胞中连接蛋白和皮质 F-肌动蛋白的募集[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 8-CPT-2'-O-Me-cAMP 相关抗体:
In Vivo	8-CPT-2'-O-Me-cAMP (2.05µM; 1 µL; intravitreal injection) 可抑制激光损伤模型中脉络膜新生血管病变的发展[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
CAS	510774-50-2
Formula	C17H17ClN5O6PS
Molar Mass	485.84
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Wittchen ES, et al. Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo. PLoS One. 2013 Sep 10;8(9):e73070.

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