Bioactivity | EGFR/HER2-IN-14 (Compd 46) is an inhibitor of mutant EGFR/HER2s which are resistant to other drugs. EGFR/HER2-IN-14 can be used for cancer research[1]. |
Invitro | EGFR/HER2-IN-14 对转染 EGFR exon 20 insASV/insSVD, HER2 exon 20 insGSP/insYVMA 突变 EGFR/HER2 的 Ba/F3 细胞的 IC50 低于 100 nM [1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> EGFR/HER2-IN-14 相关抗体: |
CAS | 3034701-54-4 |
Formula | C32H29N7O4 |
Molar Mass | 575.62 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. John H, et al. Inhibitors of egfr or her2 and methods of use. WO2024073745A1. 2024-04-04 |