| Bioactivity | EGFR/HER2-IN-10 (compound 9F) is a potent and selective dual EGFR/HER2 inhibitor with IC50s of 2.3 nM and 234 nM for EGFR and HER2, respectively. EGFR/HER2-IN-10 shows an effective antiproliferative action against prostate carcinoma[1]. |
| Name | EGFR/HER2-IN-10 |
| CAS | 2931499-82-8 |
| Formula | C29H24ClF3N6O5 |
| Molar Mass | 628.99 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Seohyun Son, et al. Development of new TAK-285 derivatives as potent EGFR/HER2 inhibitors possessing antiproliferative effects against 22RV1 and PC3 prostate carcinoma cell lines. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2202358. |
EGFR/HER2-IN-10
CAS: 2931499-82-8 F: C29H24ClF3N6O5 W: 628.99
EGFR/HER2-IN-10 (compound 9F) is a potent and selective dual EGFR/HER2 inhibitor with IC50s of 2.3 nM and 234 nM for EGF
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