| Bioactivity | EGFR T790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, targeting mutant EGFRT790M/L858R with IC50 of 56.8 μM. The anti-proliferative effect of EGFR T790M/L858R-IN-8 on cancer cell lines A549, A431, and NHI-H1975 is not significant[1]. |
| Target | IC50: 56.8 μM (EGFRT790M/L858R) |
| CAS | 333419-97-9 |
| Formula | C16H11BrN2O3 |
| Molar Mass | 359.17 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bai F, et al. Discovery of novel selective inhibitors for EGFR-T790M/L858R. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1365-70. |
EGFR T790M/L858R-IN-8
CAS: 333419-97-9 F: C16H11BrN2O3 W: 359.17
EGFR T790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, targeting mutant EGFRT790M/L858R with IC50 of 56.8 μM
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.