Bioactivity | EAPB 02303 is a microtubule-disrupting agent and inhibitor. EAPB 02303 induces mitosis arrest and impairment of spindle assembly. Thus, EAPB 02303 induces apoptosis and exhibits antitumor activity. EAPB 02303 also exhibits a potent synergy with Paclitaxel (HY-B0015) at lower concentrations[1]. |
Name | EAPB 02303 |
CAS | 1958290-51-1 |
Formula | C17H14N4O2 |
Molar Mass | 306.32 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bigot K, et al. Imiqualines for pancreatic cancer: first-in-class potent and synergistic inhibitors of microtubule polymerisation[J]. Cancer Research, 2023, 83(7_Supplement): 5729-5729. |