Bioactivity | E3 Ligase Ligand-linker Conjugate 157 is the conjugate composed of the E3 ligase ligand and the linker. E3 Ligase Ligand-linker Conjugate 157 can be used for synthesis of PROTAC degrader KT-253 (HY-170451)[1]. |
CAS | 2502189-47-9 |
Formula | C18H22N4O3 |
Molar Mass | 342.39 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Chutake YK, et al., KT-253, A Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy Than MDM2 Small Molecule Inhibitors. Mol Cancer Ther. 2024 Dec 9. |