| Bioactivity | Dual AChE-MAO B-IN-2 is a potent AChE and MAO B dual inhibitor with IC50s of 0.12 µM and 0.01 µM for b>AChE and MAO B, respectively. Dual AChE-MAO B-IN-2 has the potential for the research of Alzheimer’s disease[1]. |
| Invitro | Dual AChE-MAO B-IN-2 (compound 1) shows a +5.5 °C increase in the MAO B enzyme Tm value[1]. |
| Name | Dual AChE-MAO B-IN-2 |
| CAS | 1801157-64-1 |
| Formula | C26H25NO4 |
| Molar Mass | 415.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ekström F, et al. Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures. ACS Med Chem Lett. 2022, 13(3):499-506. |
Dual AChE-MAO B-IN-2
CAS: 1801157-64-1 F: C26H25NO4 W: 415.48
Dual AChE-MAO B-IN-2 is a potent AChE and MAO B dual inhibitor with IC50s of 0.12 µM and 0.01 µM for b>AChE and MAO B,
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This product is for research use only, not for human use. We do not sell to patients.