| Bioactivity | Dopamine D4 receptor antagonist-1 is a selective DRD4 antagonists, with a Ki of 9.0 nM for Hd4.2. Dopamine D4 receptor antagonist-1 can be used in study of schizophrenia[1]. |
| In Vivo | Dopamine D4 receptor antagonist-1 (10 mg/kg; i.p.; single) shows inhibitory effect on catecholaminergic systems (DOPA accumulation in the hippocampus)[1]. Animal Model: |
| Name | Dopamine D4 receptor antagonist-1 |
| CAS | 444724-92-9 |
| Formula | C18H19ClN4 |
| Molar Mass | 326.82 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pugsley TA, et al. The discovery of PD 89211 and related compounds: selective dopamine D4 receptor antagonists. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Feb;26(2):219-26. |
Dopamine D4 receptor antagonist-1
CAS: 444724-92-9 F: C18H19ClN4 W: 326.82
Dopamine D4 receptor antagonist-1 is a selective DRD4 antagonists, with a Ki of 9.0 nM for Hd4.2. Dopamine D4 receptor a
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