| Bioactivity | Dihydromaniwamycin E is a heat-shock metabolite with antiviral activity against influenza and SARS-CoV-2 viruses[1]. |
| Target | Influenza, SARS-CoV-2 |
| Invitro | Dihydromaniwamycin E shows an inhibitory effect against influenza (H1N1) virus infection in MDCK cells by a plaque assay, exhibiting an IC50 of 25.7 μM[1].Dihydromaniwamycin E displays antiviral activity against SARS-CoV-2, the causative agent of COVID-19 infection, in 293TA cells, exhibiting an IC50 of 19.7 μM[1]. |
| Name | Dihydromaniwamycin E |
| Formula | C10H22N2O2 |
| Molar Mass | 202.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Saito S, et al. Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses. J Nat Prod. 2022 Oct 12:acs.jnatprod.2c00550. |