| Bioactivity | Detomidine, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine produces dose-dependent analgesic effects[1][2]. |
| Invitro | Currently, detomidine is only licenced for use in horses. α2-adrenergic agonists produce dose-dependent analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action. |
| Name | Detomidine |
| CAS | 76631-46-4 |
| Formula | C12H14N2 |
| Molar Mass | 186.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |