| Bioactivity | 4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2-mediated phenacetin O-deethylation with an IC50 value of 1.7μM and a Ki value of 2.6 μM. 4,5-Dimethoxycanthin-6-one, as an alkaloid, is isolated from the wood of Picrasma quassioides BENNET (Simaroubaceae)[1][2]. |
| Invitro | 4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2-mediated phenacetin O-deethylation with an IC50 value of 1.7μM and a Ki value of 2.6 μM[2]. |
| Name | 4,5-Dimethoxycanthin-6-one |
| CAS | 18110-87-7 |
| Formula | C16H12N2O3 |
| Molar Mass | 280.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
4,5-Dimethoxycanthin-6-one
CAS: 18110-87-7 F: C16H12N2O3 W: 280.28
4,5-Dimethoxycanthin-6-one is a potent and uncompetitive inhibitor of CYP1A2-mediated phenacetin O-deethylation with an
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.