| Bioactivity | Depudecin ((-)-Depudecin) is a histone deacetylase (HDAC) inhibitor. Depudecin can be isolated from the fungus Alternaria brassicicola[1][2]. |
| Invitro | Depudecin (48 h) 可以诱导由 ras 和 src 癌基因双重转化的 NIH3T3 细胞的扁平表型[1]。 |
| Name | Depudecin |
| CAS | 139508-73-9 |
| Formula | C11H16O4 |
| Molar Mass | 212.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hannah T Reynolds, et al. Differential Retention of Gene Functions in a Secondary Metabolite Cluster. Mol Biol Evol. 2017 Aug 1;34(8):2002-2015. [2]. M Matsumoto, et al. Depudecin: a novel compound inducing the flat phenotype of NIH3T3 cells doubly transformed by ras- and src-oncogene, produced by Alternaria brassicicola. J Antibiot (Tokyo). 1992 Jun;45(6):879-85. |