Bioactivity | Dafphedyn is an analogue of Dynorphin (1-13). Dafphedyn has diuretic and profound analgesia effects that can be antagonized by centrally administered Naltrexone (HY-76711) or Naloxone (HY-17417A)[1]. |
In Vivo | Dafphedyn (5-40 μg, 脑室注射, 一次) 在雄性 Sprague-Dawley 大鼠中以剂量依赖性方式诱导深度镇痛[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 111846-43-6 |
Sequence | Tyr-{d-Ala}-Gly-{Phe(F5)}-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-NH2 |
Shortening | Y-{d-Ala}-G-{Phe(F5)}-LRRIRPKLK-NH2 |
Formula | C76H124F5N25O14 |
Molar Mass | 1706.95 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Walker JM, et al. [D-Ala2, (F5) Phe4]-dynorphin 1-13-NH2 (DAFPHEDYN): a potent analog of dynorphin 1-13. Peptides. 1987 Sep-Oct;8(5):811-7. |