| Bioactivity | DV1 is a selective antagonist for CXC chemokine receptor 4 (CXCR4). DV1 exhibits antiviral activity by blocking HIV-1 entry through the CXCR4 co-receptor. DV1 is stable in rats plasama and exhibits good pharmacokinetic characters in rat model[1]. |
| Sequence | d-(Leu-Gly-Ala-Ser-Trp-His-Arg-Pro-Asp-Lys-Cys-Cys-Leu-Gly-Tyr-Gln-Lys-Arg-Pro-Leu-Pro)-NH2 |
| Shortening | d-(LGASWHRPDKCCLGYQKRPLP)-NH2 |
| Formula | C108H170N34O26S2 |
| Molar Mass | 2424.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhu Y, et al., LC-MS/MS assay for the determination of a novel D-peptide antagonist of CXCR4 in rat plasma and its application to a preclinical pharmacokinetic study. J Pharm Biomed Anal. 2018 Nov 30;161:159-167. |