| Bioactivity | DPP-4/GPR119 modulator 1 (Compound 22) is an orally active dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist. DPP-4/GPR119 modulator 1 shows blood glucose-lowering effect and moderate inhibition on hERG channel with an IC50 of 4.9 µM. DPP-4/GPR119 modulator 1 can be used for diabetes research[1][1]. |
| Target | IC50: 4.9 µM (hERG) |
| Name | DPP-4/GPR119 modulator 1 |
| CAS | 2411099-68-6 |
| Formula | C30H39ClN10O3 |
| Molar Mass | 623.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li G, et al. The optimization of xanthine derivatives leading to HBK001 hydrochloride as a potent dual ligand targeting DPP-IV and GPR119. Eur J Med Chem. 2020 Feb 15;188:112017. |
DPP-4/GPR119 modulator 1
CAS: 2411099-68-6 F: C30H39ClN10O3 W: 623.15
DPP-4/GPR119 modulator 1 (Compound 22) is an orally active dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist
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