Bioactivity | DPC-AJ1951, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 in ex vivo and in vivo assays of bone resorption[1]. |
Invitro | DPC-AJ1951 induces intracellular Ca2+ mobilization in HEK 293 cells transfected with the human PPR (EC50 26±14 nM)[1][1]. |
Name | DPC-AJ1951 |
CAS | 943519-33-3 |
Shortening | {Aib}V{Aib}EIQL{Nle}HQRAKY-NH2 |
Formula | C76H127N23O19 |
Molar Mass | 1666.99 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Percy H Carter, et al. Discovery of a Small Molecule Antagonist of the Parathyroid Hormone Receptor by Using an N-terminal Parathyroid Hormone Peptide Probe. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6846-51. |