| Bioactivity | DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potential for the research of cancer[1]. | ||||||||||||
| Invitro | 当添加 5 mM GSH 或 0.01% Triton-X 时，DP00477 对 IDO1 抑制性的 IC50 值分别为 71, 6.3 µM[1]。 | ||||||||||||
| Name | DP00477 | ||||||||||||
| CAS | 169120-56-3 | ||||||||||||
| Formula | C17H11ClF3N3OS | ||||||||||||
| Molar Mass | 397.80 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Röhrig UF, et al. Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. Eur J Med Chem. 2014 Sep 12;84:284-301. |
DP00477
CAS: 169120-56-3 F: C17H11ClF3N3OS W: 397.80
DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 µM. DP00477 has the potent
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