Bioactivity | DNMT1-IN-3 (compound 7t-S) is a DNMT1 inhibitor with the IC50 of 0.777 μM. DNMT1-IN-3 induces cell apoptosis and causes G0/G1 phase arrest[1]. |
CAS | 3025012-68-1 |
Formula | C23H13Cl3N2O4 |
Molar Mass | 487.72 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Liu J, et al. Identification of 3-(9H-carbazol-9-yl)-2-(1,3-dioxoisoindolin-2-yl)propanoic acids as promising DNMT1 inhibitors. Eur J Med Chem. Published online May 27, 2024. |