| Bioactivity | DNMT-IN-1 is a potent DNMT inhibitor with an EC50 value of 3.2 µM. DNMT-IN-1 shows antiproliferative active[1]. |
| Invitro | DNMT-IN-1 (compound 3b) 具有抗增殖活性，对 KG1、HCT116 细胞的 EC50 分别为 13.0、10.7 µM[1]。 Cell Proliferation Assay[1] Cell Line: |
| Name | DNMT-IN-1 |
| CAS | 2396691-28-2 |
| Formula | C15H9BrN2O6 |
| Molar Mass | 393.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pechalrieu D, et al. Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells. Eur J Med Chem. 2020 Jan 15;186:111829. |