| Bioactivity | DNA gyrase B-IN-1 (compound 13) is a potent DNA gyrase B inhibitor. DNA gyrase B-IN-1 shows inhibition of P. aeruginosa DNA gyrase B, with an IC50 of 2.2 μM. DNA gyrase B-IN-1 has good binding affinity and stability[1]. |
| Target | IC50: 2.2 ± 0.08 μM (Pa DNA gyrase B) |
| Name | DNA gyrase B-IN-1 |
| Formula | C23H18ClF3N6O4S |
| Molar Mass | 566.94 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jogula S, et al. Design, synthesis and biological evaluation of novel Pseudomonas aeruginosa DNA gyrase B inhibitors. Bioorg Chem. 2020 Jul;100:103905. |
DNA gyrase B-IN-1
CAS: F: C23H18ClF3N6O4S W: 566.94
DNA gyrase B-IN-1 (compound 13) is a potent DNA gyrase B inhibitor. DNA gyrase B-IN-1 shows inhibition of P. aeruginosa
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