Bioactivity | DGKζ-IN-6 (compound 40) is an oral active DGKζ inhibitor with the IC50 of 45.5 nM. DGKζ-IN-6 inhibits the secretion of IL-2 and can be used for study of cancer and autoimmune diseases[1]. |
CAS | 3058005-75-4 |
Formula | C22H21FN4O3S |
Molar Mass | 440.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xie Yuli, et al. Thiazole compounds as DGKζ inhibitors. China, WO2024208198A1. 2024-10-10 |