| Bioactivity | DGKα-IN-3 (example 25) is a DGKα inhibitor with the IC50 of 283 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study. |
| Target | 283 nM (DGKα) |
| Name | DGKα-IN-3 |
| CAS | 2648418-86-2 |
| Formula | C26H27F3N4O3 |
| Molar Mass | 500.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Schmees, Norbert, et al. Preparation of substituted aminoquinolones as DGKα inhibitors for immune activation. WO2021105115. |
DGKα-IN-3
CAS: 2648418-86-2 F: C26H27F3N4O3 W: 500.51
DGKα-IN-3 (example 25) is a DGKα inhibitor with the IC50 of 283 nM, extracted from patent WO2021105115. DGKα-IN-2 sig
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