| Bioactivity | DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study. |
| Target | 0.9 nM (DGKα) |
| Name | DGKα-IN-2 |
| CAS | 2648556-92-5 |
| Formula | C23H22F3N3O4 |
| Molar Mass | 461.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Schmees, Norbert, et al. Preparation of substituted aminoquinolones as DGKα inhibitors for immune activation. WO2021105115. |
DGKα-IN-2
CAS: 2648556-92-5 F: C23H22F3N3O4 W: 461.43
DGKα-IN-2 (example 48) is a DGKα inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKα-IN-2 sig
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