| Bioactivity | DCLK1-IN-2 (compound I-5) is a potent DCLK1 inhibitor with an IC50 of 171.3 nM. DCLK1-IN-2 shows remarkable antiproliferative effects on SW1990 cell lines (IC50 of 0.6 μM) and in vivo antitumor potency[1]. |
| Name | DCLK1-IN-2 |
| CAS | 2978517-43-8 |
| Formula | C26H32N8O3S |
| Molar Mass | 536.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yuepeng Chen, et al. Design, synthesis and biological evaluation of novel DCLK1 inhibitor containing purine skeleton for the treatment of pancreatic cancer. European Journal of Medicinal Chemistry. 7 October 2023, 115846. |