D-Leu-Pro-Arg-Rh110-D-Pro TFA_product_DataBase

CAS: F: C42H51N9O7.xC2HF3O2 W: 793.91 (free base)

D-Leu-Pro-Arg-Rh110-D-Pro TFA is a substrate for Factor Xa I (FXIa) with binding affinity. D-Leu-Pro-Arg-Rh110-D-Pro TFA

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	D-Leu-Pro-Arg-Rh110-D-Pro TFA is a substrate for Factor Xa I (FXIa) with binding affinity. D-Leu-Pro-Arg-Rh110-D-Pro TFA consists of Rhodamine 110 (HY-D0817) linked to a peptide chain through a cleavable bond. Cleavable bond cleavage enhances fluorophore intensity. D-Leu-Pro-Arg-Rh110-D-Pro TFA can be used to detect FXIa activity[1].
Name	D-Leu-Pro-Arg-Rh110-D-Pro TFA
Sequence	{d-Leu}-Pro-Arg-{Rh110}-{d-Pro}
Shortening	{d-Leu}-PR-{Rh110}-{d-Pro}
Formula	C42H51N9O7.xC2HF3O2
Molar Mass	793.91 (free base)
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Lorthiois E, et al. Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J Med Chem. 2020 Aug 13;63(15):8088-8113.

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