Bioactivity | Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC50 values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems[1]. |
Target | IC50: 1.699 mM (HeLa cell) and 0.358 mM (MCF-7 cell). |
Invitro | Cyclo(Gly-His) 对 HeLa 和 MCF-7 细胞具有细胞毒性,IC50 值分别为 1.699 mM 和 0.358 mM[1]。 |
Name | Cyclo(Gly-His) |
CAS | 15266-88-3 |
Sequence | Cyclo(Gly-His) |
Shortening | Cyclo(GH) |
Formula | C8H10N4O2 |
Molar Mass | 194.19 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kilian G, et al. Anticancer activity of the liposome-encapsulated cyclic dipeptides, cyclo(His-Gly) and cyclo(His-Ala). Pharmazie. 2013;68(3):207-211. |