| Bioactivity | Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research[1][2][3][4]. |
| Invitro | Cyclic-di-GMP disodium (0.5-50 µM; 5 days) inhibits proliferation of human colon cancer cells[1].Cyclic-di-GMP disodium (0.5-50 µM; 5 days) specifically elevates CD4 expression in Jurkat cells[2].Cyclic-di-GMP disodium (0.5-50 µM; 5 days) induces cell cycle arrest at the S-phase in Jurkat cells[2]. Cell Proliferation Assay[1] Cell Line: |
| Name | Cyclic-di-GMP disodium |
| CAS | 2222132-40-1 |
| Formula | C20H22N10Na2O14P2 |
| Molar Mass | 734.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -80°C, protect from light, stored under nitrogen |
Cyclic-di-GMP disodium
CAS: 2222132-40-1 F: C20H22N10Na2O14P2 W: 734.37
Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacteri
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