| Bioactivity | Cuspin-1 is a upregulator of Survival of Motor Neuron protein (SMN). Cuspin-1 upregulates SMN expression post-transcriptionally, and increases the phosphorylation of Erk. Cuspin-1 can be used for research of neurodegenerative disease, such as spinal muscular atrophy (SMA)[1]. |
| CAS | 337932-29-3 |
| Formula | C13H10BrNO |
| Molar Mass | 276.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Letso RR, et al. Small molecule screen reveals regulation of survival motor neuron protein abundance by Ras proteins. ACS Chem Biol. 2013 May 17;8(5):914-22. |