| Bioactivity | Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin. Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis[1]. | ||||||||||||
| Target | IC50: glucocorticoid | ||||||||||||
| In Vivo | Clobetasone butyrate (application on the skin; 0.05%; 7 weeks) induces epidermal thinning in skin, Clobetasone butyrate 7 weeks causes much less epidermal thinning in the pig than flurandrenolone (0.05%) or fluocinolone acetonide (0.025%), both of which causes severe atrophy[1]. Animal Model: | ||||||||||||
| Name | Clobetasone butyrate | ||||||||||||
| CAS | 25122-57-0 | ||||||||||||
| Formula | C26H32ClFO5 | ||||||||||||
| Molar Mass | 478.98 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Munro DD, et al. Clobetasone butyrate, a new topical corticosteroid: clinical activity and effects on pituitary-adrenal axis function and model of epidermal atrophy. [2]. Michael Stewart, et al. Clobetasone butyrate for inflammatory skin conditions. |
Clobetasone butyrate
CAS: 25122-57-0 F: C26H32ClFO5 W: 478.98
Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin. Clobet
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.