| Bioactivity | Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against HRV at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion[1]. |
| Target | Human rhinovirus |
| Name | Citrullinated LL-37 4cit |
| Sequence | Leu-Leu-Gly-Asp-Phe-Phe-{Cit}-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-{Cit}-Ile-Val-Gln-{Cit}-Ile-Lys-Asp-Phe-Leu-{Cit}-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser |
| Shortening | LLGDFF-{Cit}-KSKEKIGKEFK-{Cit}-IVQ-{Cit}-IKDFL-{Cit}-NLVPRTES |
| Formula | C205H336N56O57 |
| Molar Mass | 4497.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Casanova V, et al. Citrullination Alters the Antiviral and Immunomodulatory Activities of the Human Cathelicidin LL-37 During Rhinovirus Infection. Front Immunol. 2020 Feb 4;11:85. |
Citrullinated LL-37 4cit
CAS: F: C205H336N56O57 W: 4497.20
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activ
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