Bioactivity | Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on B. mori GABAR RDL with an IC50 of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50 of 1.66 nM. Chrodrimanin B, a meroterpenoid, shows insecticidal activity[1]. |
Invitro | Chrodrimanin B exhibits much weaker blocking action on human α1β2γ2 GABAR compared to RDL (IC50=1.48 μM)[1]. Chrodrimanin B shows competitive actions at low concentrations and non-competitive actions at higher concentrations on B. mori GABAR RDL[1]. |
Name | Chrodrimanin B |
CAS | 132196-54-4 |
Formula | C27H32O8 |
Molar Mass | 484.54 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |