PeptideDB

Chrodrimanin B

CAS: 132196-54-4 F: C27H32O8 W: 484.54

Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on B. mori GABAR RDL with
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Bioactivity Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on B. mori GABAR RDL with an IC50 of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50 of 1.66 nM. Chrodrimanin B, a meroterpenoid, shows insecticidal activity[1].
Invitro Chrodrimanin B exhibits much weaker blocking action on human α1β2γ2 GABAR compared to RDL (IC50=1.48 μM)[1]. Chrodrimanin B shows competitive actions at low concentrations and non-competitive actions at higher concentrations on B. mori GABAR RDL[1].
Name Chrodrimanin B
CAS 132196-54-4
Formula C27H32O8
Molar Mass 484.54
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.