| Bioactivity | ChREBPα/14-3-3 regulator-1 (Compound 43) is a selective molecular gel that can stabilize the interaction of carbohydrate response element binding protein (ChREBP) with 14-3-3 proteins (EC50: 3.8 μM). ChREBPα/14-3-3 regulator-1 effectively protects β cells from glucolipotoxicity and maintains cell function, and can be used in the study of type 2 diabetes[1]. |
| Formula | C16H15F3NO5P |
| Molar Mass | 389.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Katz LS, et al. Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity. bioRxiv [Preprint]. 2024 Nov 17:2024.02.16.580675. |
ChREBPα/14-3-3 regulator-1
CAS: F: C16H15F3NO5P W: 389.26
ChREBPα/14-3-3 regulator-1 (Compound 43) is a selective molecular gel that can stabilize the interaction of carboh
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.