| Bioactivity | Ceftolozane (CXA-101 free base; FR264205 free base) is a cephalosporin antibiotic with potent activity againstPseudomonas aeruginosa and strains Enterobacteriaceae, with MICs of 0.5 and 0.25-0.5 mg/L[1]. | ||||||||||||
| In Vivo | Ceftolozane (25 mg/kg) 在受感染的中性粒减少小鼠中的半衰期是 11.6 分钟，清除率是 25.2 μg/mL[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
| CAS | 689293-68-3 | ||||||||||||
| Formula | C23H30N12O8S2 | ||||||||||||
| Molar Mass | 666.69 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Craig WA, et al., In vivo activities of ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum β-lactamases, in the thighs of neutropenic mice. Antimicrob Agents Chemother. 2013 Apr;57(4):1577-82. |
Ceftolozane
CAS: 689293-68-3 F: C23H30N12O8S2 W: 666.69
Ceftolozane (CXA-101 free base; FR264205 free base) is a cephalosporin antibiotic with potent activity againstPseudomona
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