Bioactivity | Antibacterial agent 201 (Compound 3) is an antibacterial agent through disruption of membrane integrity. Antibacterial agent 201 inhibits proliferation of Staphylococcus aureus strain RN4220, methacillin-resistane S. aureus, Pseudomonas aeruginosa strain PA01 and Escherichia coli strain ANS1 with MIC99s of 2.0, 1, 8.1 and 2.2 μg/mL, respectively[1]. |
Invitro | Antibacterial agent 201 (0-100 μg/mL) 对癌细胞 A549 和 HEK293T 具有细胞毒性,CC50 分别为 64 和 32 μg/mL[1]。Antibacterial agent 201 (1-4 μg/mL) 与 Kanamycin (HY-16566) 发挥协同作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antibacterial agent 201 相关抗体: Cell Cytotoxicity Assay[1] Cell Line: |
CAS | 1666171-29-4 |
Formula | C41H54N6S2 |
Molar Mass | 695.04 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang B, et al., Antibacterial Diamines Targeting Bacterial Membranes. J Med Chem. 2016 Apr 14;59(7):3140-51. |