| Bioactivity | Cbl-b-IN-10 (Compound 463) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.0 nM and 3.5 nM, respectively[1]. |
| Target | IC50: 3.5 nM (c-Cbl), 6.0 nM (Cbl-b) |
| Name | Cbl-b-IN-10 |
| CAS | 2815225-12-6 |
| Formula | C31H37F3N6O |
| Molar Mass | 566.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1. |