Caspase-3/7 activator 1_product_DataBase

Bioactivity	Caspase-3/7 activator 1 is an effective activator of Caspase-3/7. Caspase-3/7 activator 1 has tumor selectivity, anti-proliferative activity and high Apoptosis-inducing ability[1].
Invitro	Caspase-3/7 activator 1 (Compound 7a) 对 Wi-38、Caco-2 和 HepG-2 细胞有抑制作用，IC50 值分别为 11.195 µM、0.088 µM、0.115 µM[1]。Caspase-3/7 activator 1 (0.06 μM；72 h) 显著抑制 Caco-2 细胞凋亡抑制物 Bcl2 的表达 (下调 Bcl2 0.471 倍)。Caspase-3/7 activator 1 对 Caco-2 和 HepG-2 细胞形态无显著影响[1]。Caspase-3/7 activator 1 (0.088 µM；72 h) 有诱导 Caco-2 细胞凋亡的潜力 (凋亡细胞总数为 50.905 %)[1]。 Apoptosis Analysis[1] Cell Line:
Name	Caspase-3/7 activator 1
Formula	C26H28N2O5
Molar Mass	448.51
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

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