| Bioactivity | Capeserod hydrochloride (SL65.0155) is a 5-HT4(e) receptor partial agonist (Ki=0.6 nM) with potent cognitive enhancing properties. Capeserod hydrochloride acts as a partial agonist in cells expressing 5-HT4(b) and 5-HT4(e) splice variants, stimulating cAMP production with IC50 values ??of 244 and 29 nM, respectively. Capeserod hydrochloride is used in the study of memory impairment and dementia[1]. |
| CAS | 191023-43-5 |
| Formula | C23H26Cl2N4O4 |
| Molar Mass | 493.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Moser P C, et al. SL65. 0155, a novel 5-hydroxytryptamine4 receptor partial agonist with potent cognition-enhancing properties[J]. Journal of Pharmacology and Experimental Therapeutics, 2002, 302(2): 731-741. |
Capeserod hydrochloride
CAS: 191023-43-5 F: C23H26Cl2N4O4 W: 493.38
Capeserod hydrochloride (SL65.0155) is a 5-HT4(e) receptor partial agonist (Ki=0.6 nM) with potent cognitive enhancing p
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