Bioactivity | BG14 is a chemical optical modulation of epigenetic regulation of transcription (COMET) probe. BG14 enables high-resolution optical control of epigenetic mechanisms using visible light and can photochromically inhibit human histone deacetylases (HDACs). BG14 can be used to study the dynamic regulation of the human genome[1]. |
CAS | 1628784-50-8 |
Formula | C21H21N5O |
Molar Mass | 359.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Reis S A, et al. Light-controlled modulation of gene expression by chemical optoepigenetic probes[J]. Nature chemical biology, 2016, 12(5): 317-323. |