| Bioactivity | Calpain inhibitors are lipophilic and show moderate to good antiproliferative activity in vitro compared with melanoma cell lines (a-375 and b-16f1) and PC-3 prostate cancer cells. In addition, a member of this group (compound 3) expressed 2 μ M concentration inhibited the invasion of DU-145 cells by 80%. |
| Name | Calpain Inhibitor-2 |
| CAS | 2413962-65-7 |
| Formula | C26H33N3O5S |
| Molar Mass | 499.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Donkor IO,et al. Synthesis and antiproliferative activity of sulfonamide-based peptidomimetic calpain inhibitors. Bioorg Med Chem. 2020 May 1;28(9):115433. |
Calpain Inhibitor-2
CAS: 2413962-65-7 F: C26H33N3O5S W: 499.62
Calpain inhibitors are lipophilic and show moderate to good antiproliferative activity in vitro compared with melanoma c
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