Bioactivity | CYP51-IN-17 (compound 7a) is a potent CYP51 inhibitor with an IC50 of 0.377 μg/mL. CYP51-IN-17 shows significant fungicidal activity against B. cinerea with an EC50 of 0.326 μg/mL[1]. |
Formula | C24H20N2O7 |
Molar Mass | 448.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bao A, et al. Design, Synthesis, Bioactive Evaluation, and Molecular Dynamics Simulation of Novel 4 H-Pyrano [3, 2-c] pyridine Analogues as Potential Sterol 14α-Demethylase (CYP51) Inhibitors[J]. Journal of Medicinal Chemistry, 202 |